Brushing teeth frequently is linked with lower risks of atrial fibrillation and heart failure, according to a study published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).
Daytime napping may benefit heart health
Positive Phase III Trial Results for Potential Lupus Nephritis Treatment
Humans and autoimmune diseases continue to evolve together
The ability to fight disease is a driving force in human survival. Inflammation has emerged as a key weapon in this process. As pathogens change and evolve, the immune system adapts to keep up.
However, to what extent might such evolutionary adaptations also give rise to autoimmune conditions such as lupus and Crohn's disease?
Hair loss in systemic lupus may indicate active disease
Kidney transplant improves survival rates in patients with Lupus Nephritis
Malaria research advances immunotherapy in lupus
A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus. The research showed, in laboratory models, that strong inflammatory signals caused by malaria infection activate molecules that trigger B cells to produce highly potent antibodies to fight the disease.
More than half of males with lupus report feeling depressed, receive little support.
Researchers at Hospital for Special Surgery (HSS) in New York City launched the nationwide survey to assess the needs of male patients and found that 58% reported feeling depressed for several days or more than half the days in the previous two weeks. Regarding support and coping, 52% reported that they received no support. More than 80% of respondents indicated that lupus limited their activities of daily living, mostly due to pain and fatigue.
High Doses of Hydroxychloroquine May Protect Against Thrombosis in SLE
Higher prescribed doses of hydroxychloroquine (HCQ) may be associated with lower odds of thrombotic events in patients with systemic lupus erythematosus (SLE), according to study results presented at the 2019 The American College of Rheumatology/Association of Rheumatology Professionals (ACR/ARP) Annual Meeting, held November 8 to 13, 2019, in Atlanta, Georgia.
Lupus patients are 3 times more likely to use opioids to control pain
Secondary Sjögren's syndrome impacts quarter of patients with SLE
Study Finds Blood Levels of Plaquenil may be Important Indicator of Eye Disease Risk
Role of gut microbiota studied in pregnant women with lupus
A new study shows that pregnancy and breastfeeding could change the way the body reacts to conventional lupus treatment in women due to imbalances in the gut bacterial community, or dysbiosis. The research was undertaken to understand the higher risk of severe flares and help women with lupus experience healthy pregnancies and successful outcomes, by improving therapeutic approaches.
Researchers Identify Genetic Marker for Lupus in African American Women
A new study published in the journal Arthritis & Rheumatology finds there may be a genetic explanation for the development of systemic lupus erythematosus (SLE) in African American women.
The study, published on August 20, points to epigenetic changes near interferon-regulated genes early in B cell development. These changes are a “hallmark” of SLE development in African American women, the authors wrote.
“We have identified an aberrant epigenetic signature that developed early in B cell development in African American patients. This observation is consistent with recently published work which identified a SLE-specific epigenetic signature present in the resting naïve B cell stage that persists throughout development in a cohort of Africa American females,” wrote the authors who were led by Devin Absher, Ph.D., of the HudsonAlpha Institute for Biotechnology in Alabama.
New study shows statins ineffective at fighting cardiovascular disease in Lupus patients
Epstein-Barr virus may be a possible trigger for the development of lupus
Oklahoma Medical Research Foundation (OMRF) scientists have discovered that the Epstein-Barr virus may be a possible trigger for the development of lupus in at-risk individuals.
Scientists have long known lupus has a strong genetic component, but there also must be environmental triggers to activate the disease.
Cognitive and Psychiatric Issues Linked to Autoantibodies in Brain Unique to Lupus Patients, study finds
Autoantibodies targeting certain regulatory RNAs — molecules that serve as the template for protein production — in the brains of lupus patients are unique to these people and involved in neuropsychiatric symptoms of the disease, a study reports.
The study, “Neuronal BC RNA transport impairments caused by systemic lupus erythematosus autoantibodies,” was published in the Journal of Neuroscience.
Benlysta Found to Effectively Change B-cell Levels
In a new study, researchers looked at whether treatments targeting B-cell activating factor (BAFF) have an impact on human B-cells, as previous studies have suggested. B-cells are responsible for creating antibodies, including autoantibodies, and are thought to play a role in the development and progression of autoimmune diseases.
Abnormal Blood Pressure Patterns May Predict Cardiovascular Disease in Juvenile-onset SLE
Researchers identify key mechanism linked to neuropsychiatric lupus
A breakthrough study by a SUNY Downstate Health Sciences University research team has identified a specific antibody target implicated in neuropsychiatric symptoms of lupus. These symptoms, including cognitive impairment, mood disorders, seizures, headaches and psychosis, are among the most prevalent manifestations of the disease and occur in as many as 80% of adults and 95% of children with lupus.
